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Epigenetics of discordant monozygotic twins: implications for disease

30 Jul 2014

Abstract excerpt

Monozygotic (MZ) twins share nearly all of their genetic variants and many similar environments before and after birth. However, they can also show phenotypic discordance for a wide range of traits. Differences at the epigenetic level may account for such discordances. It is well established that epigenetic states can contribute to phenotypic variation, including disease. Epigenetic states are dynamic and...

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PMID: 25484923
DOI: 10.1186/s13073-014-0060-z

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