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Article

Different effects of the TAR structure on HIV-1 and HIV-2 genomic RNA translation

24 Nov 2011

Abstract excerpt

The 5'-untranslated region (5'-UTR) of the genomic RNA of human immunodeficiency viruses type-1 (HIV-1) and type-2 (HIV-2) is composed of highly structured RNA motifs essential for viral replication that are expected to interfere with Gag and Gag-Pol translation. Here, we have analyzed and compared the properties by which the viral 5'-UTR drives translation from the genomic RNA of both human immunodeficiency...

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PMID: 22121214
DOI: 10.1093/nar/gkr1093

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