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Article

A 5'UTR-spliced mRNA isoform is specialized for enhanced HIV-2 gag translation.

Journal of molecular biology - 14 Aug 2009

Strong Christy L, Lanchy Jean-Marc, Dieng-Sarr Abdoulaye, Kanki Phyllis J, Lodmell J Stephen

Abstract excerpt

Full-length unspliced genomic RNA plays critical roles in HIV replication, serving both as mRNA for the synthesis of the key viral polyproteins Gag and Gag-Pol and as genomic RNA for encapsidation into assembling viral particles. We show that a second gag mRNA species that differs from the genomic RNA molecule by the absence of an intron in the 5' untranslated region (5'UTR) is produced during HIV-2 replication...

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Identifiers

PMID: 19559029
DOI: 10.1016/j.jmb.2009.06.046
PMCID: PMC2750851

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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