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Article

Novel animal glioma models that separately exhibit two different invasive and angiogenic phenotypes of human glioblastomas.

World neurosurgery - 1 Dec 2012

Inoue Satoshi, Ichikawa Tomotsugu, Kurozumi Kazuhiko, Maruo Tomoko, Onishi Manabu, Yoshida Koichi, Fujii Kentaro, Kambara Hirokazu, Chiocca E Antonio, Date Isao

Abstract excerpt

OBJECTIVE: Invasive behaviors of malignant gliomas are fundamental traits and major reasons for treatment failure. Delineation of invasive growth is important in establishing treatment for gliomas and experimental neuro-oncology could benefit from an invasive glioma model. In this study, we established two new cell line-based animal models of invasive glioma. METHODS: Two cell lines, J3T-1 and J3T-2, were derived...

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PMID: 22120277
DOI: 10.1016/j.wneu.2011.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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