Article
Tumor cell invasion and angiogenesis in the central nervous system.
Current opinion in oncology - 1 May 1997
Bjerkvig R, Lund-Johansen M, Edvardsen K
Abstract excerpt
Tumor cell growth and invasion within the CNS imply complex interactions among malignant cells, neural cells, and endothelial cells. Various in vitro assays have been developed to study tumor cell invasion that includes the use of cocultures between tumor spheroids and organotypic cultures of normal brain tissue. Furthermore, various animal models have been developed to study biologic characteristics of brain...
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