Article
The molecular determinants of NEDD8 specific recognition by human SENP8.
PloS one - 1 Jan 2011
Shin Yung-Cheng, Tang Siao-Jing, Chen Jou-Han, Liao Pei-Han, Chang Shih-Chung
Abstract excerpt
Although neuronal-precursor-cell-expressed developmentally downregulated protein-8 (NEDD8) and ubiquitin share the highest level of sequence identity and structural similarity among several known ubiquitin-like proteins, their conjugation to a protein leads to distinct biological consequences. In the study, we first identified the NEDD8 protein of Chlamydomonas reinhardtii (CrNEDD8) and discovered that CrNEDD8 is...
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