Article
Associations between XPC expression, genotype, and the risk of head and neck cancer.
Environmental and molecular mutagenesis - 1 May 2005
Yang Mihi, Kang Mee-Jeong, Choi Yunhee, Kim Cheong-Sik, Lee Su-Man, Park Chul-Won, Lee Hyung-Seok, Tae Kyung
Abstract excerpt
Squamous cell carcinoma of the head and neck (SCCHN) is a relatively rare cancer with a poor prognosis. In the present study, we investigated susceptibility biomarkers for SCCHN in 155 Koreans (73 SCCHN cases and 82 controls). Expression of the xeroderma pigmentosum group C (XPC) DNA-repair gene was measured by TaqMan fluorogenic real-time RT-PCR using RNA isolated from peripheral blood samples. In addition, the...
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