Article
Preliminary results on the frequency of the delta F508 mutation in cystic fibrosis patients from the USSR.
Human genetics - 1 Sept 1990
Ronchetto P, Devoto M, Puliti A, Romeo G, Sokolov B, Kalinin V N, Vorsanova S G, Krainiaia G V, Reznik B Y
Abstract excerpt
The frequency of the delta F508 mutation in a sample of 29 cystic fibrosis (CF) families from the USSR is equal to 44.8%, in agreement with previously reported haplotype data. If confirmed on a larger sample of CF patients from the USSR, this result might be indicative of the presence of a larger heterogeneity of CF mutations in the Soviet population than in other European populations.
Topics
- Cystic Fibrosis
- Gene Frequency
- Humans
- Mutation
- USSR