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Article

Frequency of the cystic fibrosis delta F508 mutation in a large sample of the French population.

Human genetics - 1 Sept 1990

Vidaud M, Ferec C, Attree O, Pascal O, Guillermit H, Ghanem N, Martin J, Moisan J P, Feingold J, Goossens M

Abstract excerpt

We have determined the frequency of the cystic fibrosis (CF) delta F508 mutation in a large sample of CF patients originating from different areas of France, including the greater Paris, Brittany, Alsace, Lorraine and Rhône-Alpes regions. A total of 422 CF chromosomes were studied, and the defect was found to account for 75% of the mutant alleles. In the course of the survey, a rare nucleotide sequence...

Topics

Cystic Fibrosis
France
Gene Frequency
Mutation
Polymorphism, Restriction Fragment Length

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1976598
DOI: 10.1007/BF02428302

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1976598-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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