Complete map of cystic fibrosis mutation DF508 frequencies in Western Europe and correlation between mutation frequencies and incidence of disease.

Article

Complete map of cystic fibrosis mutation DF508 frequencies in Western Europe and correlation between mutation frequencies and incidence of disease.

Human biology - 1 Oct 1995

Lucotte G, Hazout S, De Braekeleer M

Abstract excerpt

The frequencies of DF508, the main cystic fibrosis mutation, vary among different populations in Western Europe; they are higher in northwestern Europeans than in southeastern populations. Our new analysis is based on results from 66 different laboratories on 17,886 cystic fibrosis chromosomes (f...

Topics

Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Europe
Gene Deletion
Gene Frequency
Genetics, Population
Humans
Incidence
Mutation
Regression Analysis

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