Article
Frequency of delta F508 in a Mexican sample of cystic fibrosis patients.
Journal of medical genetics - 1 Jun 1993
Orozco L, Salcedo M, Lezana J L, Chávez M, Valdez H, Moreno M, Carnevale A
Abstract excerpt
This paper reports the frequency of the delta F508 mutation in a cohort of 50 Mexican patients with cystic fibrosis (CF). The mutation was detected by PCR mediated site directed mutagenesis. delta F508 was found in 39% of CF chromosomes, a frequency lower than that reported in Argentina and Spain...
Topics
- Adolescent
- Adult
- Base Sequence
- Child
- Child, Preschool
- Cystic Fibrosis
- DNA Mutational Analysis
- Gene Frequency
- Humans
- Infant
- Mexico
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Polymerase Chain Reaction