delta F508 frequency and associated haplotypes near the cystic fibrosis locus in the Yugoslav population.

doi:10.1007/BF02428301

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Article

delta F508 frequency and associated haplotypes near the cystic fibrosis locus in the Yugoslav population.

Human genetics - 1 Sept 1990

Simova L, Williams C, Efremov G D, Gordova-Muratovska A, Sustić S, Watson E K, Williamson R

Abstract excerpt

Chromosomes from 19 unrelated Southern Yugoslav families in which cystic fibrosis (CF) occurs were analysed for the presence of the delta F508 mutation, using polymerase chain reaction amplification followed by dot blot and polyacrylamide gel analysis. Of the 38 CF chromosomes, 15 (39.5%) carry t...

Topics

Cystic Fibrosis
Gene Frequency
Humans
Mutation
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Yugoslavia

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