Article
Allograft inflammatory factor-1 gene polymorphisms in patients with rheumatoid arthritis.
Genetic testing and molecular biomarkers - 1 May 2012
Pawlik Andrzej, Kurzawski Mateusz, Dziedziejko Violetta, Safranow Krzysztof, Paczkowska Edyta, Maslinski Wlodzimierz, Drozdzik Marek, Gawronska-Szklarz Barbara
Abstract excerpt
AIM: Allograft inflammatory factor-1 (AIF-1) is a cytoplasmic, inflammation-responsive protein. The increased expression of AIF-1 in synovial tissues and fluid from rheumatoid arthritis (RA) patients has been detected. Several single-nucleotide polymorphisms have been identified in the AIF1 gene, among them three leading to changes in amino acid sequence. The aim of this study was to examine the association...
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