Article
The dark side of cohesin: the carcinogenic point of view.
Mutation research - 1 Jan 2000
Mannini Linda, Musio Antonio
Abstract excerpt
Genome instability is a hallmark of cancer cells and how it arises is still not completely understood. Correct chromosome segregation is a pre-requisite for preserving genome integrity. Cohesin helps to ensure faithful chromosome segregation during cell cycle, however, much evidence regarding its functions have come to light over the last few years and suggest that cohesin plays multiple roles in the maintenance...
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