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Article

In vitro insulin-like growth factor I interaction with cartilage cells derived from postnatal animals.

Hormone research - 1 Jan 1990

Demarquay D, Dumontier M F, Tsagris L, Bourguignon J, Nataf V, Corvol M T

Abstract excerpt

This paper reports data on the in vitro effects of insulin-like growth factor I (IGF-I) and basic fibroblast growth factor (bFGF) on the phenotypic expression of epiphyseal chondrocytes grown in serum-free (SF) culture medium. bFGF mostly stimulates chondrocyte DNA and inhibits sulfated proteoglycan synthesis and type II collagen mRNA. On the contrary, IGF-I is poorly mitogenic but strongly stimulates protein...

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Source

Identifiers

PMID: 2210614
DOI: 10.1159/000181493

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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