Insulin-like growth factors in embryonic and fetal growth and skeletal development (Review)

Abstract excerpt

The insulin-like growth factors (IGF)-I and -II have a predominant role in fetal growth and development. IGFs are involved in the proliferation, differentiation and apoptosis of fetal cells in vitro and the IGF serum concentration has been shown to be closely correlated with fetal growth and length. IGF transcripts and peptides have been detected in almost every fetal tissue from as early in development as...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Birth, Development, and Health
• Share to Genetic Syndromes and Imprinting
• Share to Growth Hormone and Insulin-like Growth Factors