Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epithelial and mesenchymal subpopulations within normal basal breast cell lines exhibit distinct stem cell/progenitor properties.

Stem cells (Dayton, Ohio) - 1 Feb 2012

Sarrio David, Franklin Chris K, Mackay Alan, Reis-Filho Jorge S, Isacke Clare M

Abstract excerpt

It has been proposed that epithelial-mesenchymal transition (EMT) in mammary epithelial cells and breast cancer cells generates stem cell features, and that the presence of EMT characteristics in claudin-low breast tumors reveals their origin in basal stem cells. It remains to be determined, however, whether EMT is an inherent property of normal basal stem cells, and if the presence of a mesenchymal-like...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Differentiation
Share to Claudins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial Cell Adhesion Molecule

Share to Epithelial-Mesenchymal Transition

Share to Mammary Glands, Human

Share to Snail Family Transcription Factors

Share to Spheroids, Cellular

Share to Zinc Finger E-box-Binding Homeobox 1

Source

Identifiers

PMID: 22102611
DOI: 10.1002/stem.791

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epithelial and mesenchymal subpopulations within normal basal breast cell lines exhibit distinct stem cell/progenitor properties.PMID 22102611Read ↗

Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progressionSemantic proximity Read ↗

Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer.Semantic proximity Read ↗

Epithelial-Mesenchymal Transition Programs and Cancer Stem Cell Phenotypes: Mediators of Breast Cancer Therapy Resistance.Semantic proximity Read ↗

Normal Breast-Derived Epithelial Cells with Luminal and Intrinsic Subtype-Enriched Gene Expression Document Interindividual Differences in Their Differentiation CascadeSemantic proximity Read ↗

Epithelial-Mesenchymal Plasticity of Breast Cancer Stem Cells: Implications for Metastasis and Therapeutic ResistanceSemantic proximity Read ↗

Mesenchymal traits are selected along with stem features in breast cancer cells grown as mammospheres.Semantic proximity Read ↗

Stromal Signals Dominate Gene Expression Signature Scores That Aim to Describe Cancer Cell–intrinsic Stemness or Mesenchymality CharacteristicsSemantic proximity Read ↗

Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypesSemantic proximity Read ↗

Telomerase-immortalized human mammary stem/progenitor cells with ability to self-renew and differentiateSemantic proximity Read ↗

Heterogeneity of normal human breast stem and progenitor cells as revealed by transcriptional profilingSemantic proximity Read ↗

Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor SurvivalSemantic proximity Read ↗

Stromal signals dominate gene expression signature scores that aim to describe cancer-intrinsic stemness or mesenchymality characteristicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.