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Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival

28 May 2015

Abstract excerpt

Breast cancer stem cells (CSCs) are thought to drive recurrence and metastasis. Their identity has been linked to the epithelial to mesenchymal transition (EMT) but remains highly controversial since--depending on the cell-line studied--either epithelial (E) or mesenchymal (M) markers, alone or together have been associated with stemness. Using distinct transcript expression signatures characterizing the three...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26020648
DOI: 10.1371/journal.pone.0126522

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