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Article

Characterization of polybrominated diphenyl ether toxicity in Wistar Han rats and use of liver microarray data for predicting disease susceptibilities.

Toxicologic pathology - 1 Jan 2012

Dunnick June K, Brix A, Cunny H, Vallant M, Shockley K R

Abstract excerpt

The toxicity of polybrominated diphenyl ethers (PBDEs), flame-retardant components, was characterized in offspring from Wistar Han dams exposed by gavage to a PBDE mixture (DE71) starting at gestation day 6 and continuing to weaning on postnatal day (PND) 21. Offspring from the dams underwent PBDE direct dosing by gavage at the same dose as their dams from PND 12 to PND 21, and then after weaning for another...

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PMID: 22267650
DOI: 10.1177/0192623311429973
PMCID: PMC4816085

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