Article
Early life lipid profile and metabolic programming in very young children.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Jun 2015
Wijnands K P J, Obermann-Borst S A, Steegers-Theunissen R P M
Abstract excerpt
BACKGROUND AND AIMS: Lipid derangements during early postnatal life may induce stable epigenetic changes and alter metabolic programming. We investigated associations between serum lipid profiles in very young children and DNA methylation of tumor necrosis factor-alpha (TNFα) and leptin (LEP). Secondly, we explored if the maternal serum lipid profile modifies DNA methylation in the child. METHODS AND RESULTS: In...
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