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Article

Loss of receptor activity-modifying protein 3 exacerbates cardiac hypertrophy and transition to heart failure in a sex-dependent manner.

Journal of molecular and cellular cardiology - 1 Jan 2012

Barrick Cordelia J, Lenhart Patricia M, Dackor Ryan T, Nagle Elizabeth, Caron Kathleen M

Abstract excerpt

Sex differences exist in the hypertrophic response, cardiac remodeling, and transition to heart failure of hypertensive patients, and while some of these differences are likely influenced by estrogen, the genetic pathways downstream of estrogen that impact on cardioprotection have yet to be fully elucidated. We have previously shown that the cardioprotective effects of adrenomedullin (AM), an emerging clinical...

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Angiotensin II
Cardiomegaly
Cardiovascular Diseases
Gene Knockout Techniques
Heart Failure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kidney Diseases

Proto-Oncogene Proteins c-akt

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Identifiers

PMID: 22100352
DOI: 10.1016/j.yjmcc.2011.10.021
PMCID: PMC3256744

Genes

RAMP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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