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Haptoglobin genotype predicts development of coronary artery calcification in a prospective cohort of patients with type 1 diabetes.

Cardiovascular diabetology - 20 Nov 2011

Simpson Melissa, Snell-Bergeon Janet K, Kinney Gregory L, Lache Orit, Miller-Lotan Rachel, Anbinder Yefim, Rewers Marian J, Levy Andrew P

Abstract excerpt

BACKGROUND: Coronary artery disease has been linked with genotypes for haptoglobin (Hp) which modulates extracorpuscular hemoglobin. We hypothesized that the Hp genotype would predict progression of coronary artery calcification (CAC), a marker of subclinical atherosclerosis. METHODS: CAC was measured three times in six years among 436 subjects with type 1 diabetes and 526 control subjects participating in the...

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Identifiers

PMID: 22098782
DOI: 10.1186/1475-2840-10-99
PMCID: PMC3231951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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