Article
Inverse Medea as a Novel Gene Drive System for Local Population Replacement: A Theoretical Analysis
13 Apr 2011
Abstract excerpt
One strategy to control mosquito-borne diseases, such as malaria and dengue fever, on a regional scale is to use gene drive systems to spread disease-refractory genes into wild mosquito populations. The development of a synthetic Medea element that has been shown to drive population replacement in laboratory Drosophila populations has provided encouragement for this strategy but has also been greeted with caution...
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