Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Conditions for success of engineered underdominance gene drive systems

17 Jul 2017

Abstract excerpt

Engineered underdominance is one of a number of different gene drive strategies that have been proposed for the genetic control of insect vectors of disease. Here we model a two-locus engineered underdominance based gene drive system that is based on the concept of mutually suppressing lethals. In such a system two genetic constructs are introduced, each possessing a lethal element and a suppressor of the lethal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Insect symbiosis and bacterial influences
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28728996
DOI: 10.1016/j.jtbi.2017.07.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Conditions for success of engineered underdominance gene drive systemsPMID 28728996Read ↗

Population dynamics of engineered underdominance and killer-rescue gene drives in the control of disease vectorsSemantic proximity Read ↗

Dynamics of a combined medea-underdominant population transformation systemSemantic proximity Read ↗

Engineered underdominance allows efficient and economical introgression of traits into pest populations.Semantic proximity Read ↗

Dynamics of a combined medea-underdominant population transformation systemSemantic proximity Read ↗

Confinement of gene drive systems to local populations: a comparative analysis.Semantic proximity Read ↗

Genetically engineered underdominance for manipulation of pest populations: a deterministic model.Semantic proximity Read ↗

Antiviral Effectors and Gene Drive Strategies for Mosquito Population Suppression or Replacement to Mitigate Arbovirus Transmission by Aedes aegyptiSemantic proximity Read ↗

Population dynamics of underdominance gene drive systems in continuous spaceSemantic proximity Read ↗

Rescue by gene swamping as a gene drive deployment strategy.Semantic proximity Read ↗

Progress towards engineering gene drives for population controlSemantic proximity Read ↗

A killer-rescue system for self-limiting gene drive of anti-pathogen constructs.Semantic proximity Read ↗

Gene Drives Across Engineered Fitness Valleys: Modeling a Design to Prevent Drive SpilloverSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.