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Article

Multiple end joining mechanisms repair a chromosomal DNA break in fission yeast.

DNA repair - 1 Feb 2012

Li Peng, Li Jun, Li Ming, Dou Kun, Zhang Mei-Jun, Suo Fang, Du Li-Lin

Abstract excerpt

Non-homologous end joining (NHEJ) is an important mechanism for repairing DNA double-strand breaks (DSBs). The fission yeast Schizosaccharomyces pombe has a conserved set of NHEJ factors including Ku, DNA ligase IV, Xlf1, and Pol4. Their roles in chromosomal DSB repair have not been directly characterized before. Here we used HO endonuclease to create a specific chromosomal DSB in fission yeast and examined the...

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Identifiers

PMID: 22093869
DOI: 10.1016/j.dnarep.2011.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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