Article
Evaluating the performance of Affymetrix SNP Array 6.0 platform with 400 Japanese individuals.
BMC genomics - 22 Sept 2008
Nishida Nao, Koike Asako, Tajima Atsushi, Ogasawara Yuko, Ishibashi Yoshimi, Uehara Yasuka, Inoue Ituro, Tokunaga Katsushi
Abstract excerpt
BACKGROUND: With improvements in genotyping technologies, genome-wide association studies with hundreds of thousands of SNPs allow the identification of candidate genetic loci for multifactorial diseases in different populations. However, genotyping errors caused by genotyping platforms or genotype calling algorithms may lead to inflation of false associations between markers and phenotypes. In addition, the...
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