Article
Genotype calling for the Affymetrix platform.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012
Schillert Arne, Ziegler Andreas
Abstract excerpt
The analysis of high-throughput genotyping data in genome-wide association (GWA) studies has become a standard approach in genetic epidemiology. Data of high quality are crucial for the success of these studies. The first step in the statistical analysis is the generation of genotypes from signal intensities, and several approaches have been proposed for obtaining as accurate genotypes as possible. For the...
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