Article
Cytokinesis remnants define first neuronal asymmetry in vivo.
Nature neuroscience - 13 Nov 2011
Pollarolo Giulia, Schulz Joachim G, Munck Sebastian, Dotti Carlos G
Abstract excerpt
Polarization of a neuron begins with the appearance of the first neurite, thus defining the ultimate growth axis. Unlike late occurring polarity events (such as axonal growth), very little is known about this fundamental process. We show here that, in Drosophila melanogaster neurons in vivo, the first membrane deformation occurred 3.6 min after precursor division. Clustering of adhesion complex components...
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