Article
T3111C clock single nucleotide polymorphism and mood disorders: a meta-analysis.
Chronobiology international - 1 Jun 2010
Calati Raffaella, Gaspar-Barba Enrique, Yukler Adina, Serretti Alessandro
Abstract excerpt
It has been hypothesized that abnormalities in the molecular clock underlie the development of mood disorders, in the direction of higher prevalence in individuals with a reduced flexibility to adapt to important regulations of mood in response to changes in seasons, stress levels, sleep schedules, and time zones. In particular, a T/C change (rs1801260) at the 3111 position of the circadian locomotor output...
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