Article
PI-PLCβ1 gene copy number alterations in breast cancer.
Oncology reports - 1 Feb 2012
Molinari Chiara, Medri Laura, Follo Matilde Y, Piazzi Manuela, Mariani Giulia Adalgisa, Calistri Daniele, Cocco Lucio
Abstract excerpt
Deregulation of signal transduction pathways frequently confers selective biological advantages to tumors. Phosphoinositides play an essential role in numerous cellular functions and, among the enzymes implicated in these processes, phosphoinositide-specific phospholipase C β1 (PI-PLCβ1) is one of the key regulators. In the present study, a fluorescence in situ...
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