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Article

Targetable alterations in invasive pleomorphic lobular carcinoma of the breast.

Breast cancer research : BCR - 13 Jan 2021

Riedlinger Gregory M, Joshi Sonali, Hirshfield Kim M, Barnard Nicola, Ganesan Shridar

Abstract excerpt

BACKGROUND: Invasive pleomorphic lobular carcinoma (PLC) of the breast is a subtype of invasive lobular cancer which compromises approximately 1% of all epithelial breast malignancies and is characterized by higher nuclear pleomorphism and poorer prognosis than classic invasive lobular cancer (ILC). Since PLC is more aggressive than classical ILC, we examined the underlying molecular alterations in this subtype...

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Identifiers

PMID: 33441174
DOI: 10.1186/s13058-020-01385-5
PMCID: PMC7805167

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