Article
Plasmalemma permeability and necrotic cell death phenotypes after intracerebral hemorrhage in mice.
Stroke - 1 Feb 2012
Zhu Xiaoxia, Tao Luyang, Tejima-Mandeville Emiri, Qiu Jianhua, Park Juyeon, Garber Kent, Ericsson Maria, Lo Eng H, Whalen Michael J
Abstract excerpt
BACKGROUND AND PURPOSE: Traumatic and ischemic brain injury induce plasmalemma permeability and necrosis; however, no studies have examined these aspects of cellular injury in intracerebral hemorrhage models. METHODS: In vivo propidium iodide (PI) and YOYO-1 were used to assess plasmalemma damage after collagenase-induced intracerebral hemorrhage in mice. Ex vivo aspartylglutamylvalylaspartic acid, terminal...
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