Increased striatal injury and behavioral deficits after intracerebral hemorrhage in hemopexin knockout mice.

doi:10.3171/2010.10.JNS10861

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Increased striatal injury and behavioral deficits after intracerebral hemorrhage in hemopexin knockout mice.

Journal of neurosurgery - 1 Apr 2011

Chen Lifen, Zhang Xuefeng, Chen-Roetling Jing, Regan Raymond F

Abstract excerpt

OBJECT: Heme toxicity may contribute to the pathogenesis of intracerebral hemorrhage (ICH). The primary defense against extracellular heme is provided by hemopexin, a serum and neuronal glycoprotein that binds it with very high affinity and mitigates its prooxidant effect. In the present study, the authors tested the hypothesis that hemopexin knockout mice would sustain more injury after experimental ICH than...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Behavior, Animal
Share to Cerebral Hemorrhage
Share to Corpus Striatum
Share to Haptoglobins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heme

Share to Hemoglobins

Share to Motor Activity

Share to Psychomotor Performance

Source

Open in PubMed Open full text

Identifiers

PMID: 21128737
DOI: 10.3171/2010.10.JNS10861
PMCID: PMC3061252

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.