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Article

Molecular profiling of key driver genes improves staging accuracy in multifocal non-small cell lung cancer.

The Journal of thoracic and cardiovascular surgery - 1 Aug 2020

Zheng Richard, Shen Qian, Mardekian Stacey, Solomides Charalambos, Wang Zi-Xuan, Evans Nathaniel R

Abstract excerpt

OBJECTIVE: Multifocal non-small cell lung cancer has historically been separated into synchronous primary lung cancers or intrapulmonary metastases with the use of histopathology. We hypothesize that using targeted next-generation sequencing of key driver mutations in multifocal non-small cell lung cancer will improve our ability to differentiate intrapulmonary metastases from synchronous primary lung cancers....

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Identifiers

PMID: 32007245
DOI: 10.1016/j.jtcvs.2019.11.126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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