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Article

Differential impact of cytochrome 2C9 allelic variants on clopidogrel-mediated platelet inhibition determined by five different platelet function tests.

International journal of cardiology - 5 Jun 2013

Gremmel Thomas, Kopp Christoph W, Seidinger Daniela, Koppensteiner Renate, Panzer Simon, Sunder-Plassmann Raute, Mannhalter Christine, Steiner Sabine

Abstract excerpt

BACKGROUND: The antiplatelet effect of clopidogrel is subject to considerable inter-individual variations. In vitro high on-treatment residual platelet reactivity (HRPR) has been linked to cytochrome P450 (CYP) 2C19*2 carriage, and both were significantly associated with the occurrence of adverse events after coronary stenting. It has been shown that besides CYP2C19, CYP2C9 is involved in the hepatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22075408
DOI: 10.1016/j.ijcard.2011.10.010

Genes

LTA
VASP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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