Article
Distribution patterns of variability for 18 immune system genes in Amerindians--relationship with history and epidemiology.
Tissue antigens - 1 Sept 2013
Lindenau J D, Salzano F M, Guimarães L S P, Callegari-Jacques S M, Hurtado A M, Hill K R, Petzl-Erler M L, Tsuneto L T, Hutz M H
Abstract excerpt
Native American populations generally have a higher prevalence of infectious diseases than non-Native populations and this fact can induce different pressures in their immune system. We investigated the patterns of population differentiation (FST ) of 32 polymorphisms related to adaptive immune response in four Native American populations (Aché, Guarani-Kaiowá, Guarani-Ñandeva and Kaingang), and the results were...
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