Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of apolipoprotein E genotype with smoking and physical inactivity on coronary heart disease risk in men and women.

Atherosclerosis - 1 Feb 2012

Gustavsson Jaana, Mehlig Kirsten, Leander Karin, Strandhagen Elisabeth, Björck Lena, Thelle Dag S, Lissner Lauren, Blennow Kaj, Zetterberg Henrik, Nyberg Fredrik

Abstract excerpt

OBJECTIVE: Apolipoprotein E genotype (APOE) polymorphism affects lipid levels and coronary heart disease (CHD) risk. However, these associations may be modified by lifestyle factors. Therefore, we studied whether smoking, physical inactivity or overweight interact with APOE on cholesterol levels and CHD risk. METHODS: Combining two Swedish case-control studies yielded 1735 CHD cases and 4654 population controls...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chi-Square Distribution
Share to Coronary Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene-Environment Interaction

Share to Linear Models

Share to Overweight

Share to Sedentary Behavior

Share to Surveys and Questionnaires

Share to Sweden

Source

Identifiers

PMID: 22071360
DOI: 10.1016/j.atherosclerosis.2011.10.011

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of apolipoprotein E genotype with smoking and physical inactivity on coronary heart disease risk in men and women.PMID 22071360Read ↗

A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease.Semantic proximity Read ↗

APOE genotype, lipids, and coronary heart disease risk: a prospective population study.Semantic proximity Read ↗

Saturated fat intake and alcohol consumption modulate the association between the APOE polymorphism and risk of future coronary heart disease: a nested case-control study in the Spanish EPIC cohort.Semantic proximity Read ↗

Interactions Between Lifestyle-Related Factors and the ApoE Polymorphism on Plasma Lipids and ApolipoproteinsSemantic proximity Read ↗

ApoE genotype, cardiovascular risk and responsiveness to dietary fat manipulation.Semantic proximity Read ↗

Apolipoprotein E4 and coronary heart disease in middle-aged men who smoke: a prospective study.Semantic proximity Read ↗

Apolipoprotein E4 association with metabolic syndrome depends on body fatness.Semantic proximity Read ↗

Apolipoprotein E genotype, lifestyle and coronary artery disease: gene-environment interaction analyses in the UK Biobank populationSemantic proximity Read ↗

Lipid profiles reflecting high and low risk for coronary heart disease: contribution of apolipoprotein E polymorphism and lifestyle.Semantic proximity Read ↗

Apolipoprotein E genotype and the cardiovascular disease risk phenotype: impact of sex and adiposity (the FINGEN study).Semantic proximity Read ↗

FTO genotype, physical activity, and coronary heart disease risk in Swedish men and women.Semantic proximity Read ↗

Obesity modulates the association among APOE genotype, insulin, and glucose in men.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.