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Article

Genotypic characterization of herpes simplex virus DNA polymerase UL42 processivity factor.

Antiviral research - 1 Jan 2012

Burrel Sonia, Aït-Arkoub Zaïna, Agut Henri, Boutolleau David

Abstract excerpt

The herpes simplex virus (HSV) DNA polymerase is composed of the UL30 catalytic subunit and the UL42 processivity factor. The UL42 subunit increases the processivity of the polymerase along the DNA template during replication. The molecular mechanisms of HSV resistance to drugs interfering with viral DNA synthesis reported so far mainly rely on modifications of the viral thymidine kinase and DNA polymerase. We...

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PMID: 22061617
DOI: 10.1016/j.antiviral.2011.10.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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