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Article

Associations between genetic polymorphisms of insulin-like growth factor axis genes and risk for age-related macular degeneration.

Investigative ophthalmology & visual science - 25 Nov 2011

Chiu Chung-Jung, Conley Yvette P, Gorin Michael B, Gensler Gary, Lai Chao-Qiang, Shang Fu, Taylor Allen

Abstract excerpt

PURPOSE: To investigate whether insulin-like growth factor (IGF) axis genes, together with a novel dietary risk factor, the dietary glycemic index (dGI), and body mass index (BMI) affect the risk for age-related macular degeneration (AMD). METHODS: This case-control study involved 962 subjects originally recruited through the Age-Related Eye Disease Study (AREDS) Genetic Repository. After those with missing...

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Source

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Identifiers

PMID: 22058336
DOI: 10.1167/iovs.11-7782
PMCID: PMC3231967

Genes

IGF1
IGFALS
IGFBP1
IGFBP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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