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Article

Association between vitamin D status and age-related macular degeneration by genetic risk.

JAMA ophthalmology - 1 Oct 2015

Millen Amy E, Meyers Kristin J, Liu Zhe, Engelman Corinne D, Wallace Robert B, LeBlanc Erin S, Tinker Lesley F, Iyengar Sudha K, Robinson Jennifer G, Sarto Gloria E, Mares Julie A

Abstract excerpt

IMPORTANCE: Deficient 25-hydroxyvitamin D (25[OH]D) concentrations have been associated with increased odds of age-related macular degeneration (AMD). OBJECTIVE: To examine whether this association is modified by genetic risk for AMD and whether there is an association between AMD and single-nucleotide polymorphisms of genes involved in vitamin D transport, metabolism, and genomic function. DESIGN, SETTING, AND...

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Identifiers

PMID: 26312598
DOI: 10.1001/jamaophthalmol.2015.2715
PMCID: PMC4841267

Genes

CFH
CFI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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