Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of Aging on Superovulation Efficiency, Aneuploidy Rates, and Sister Chromatid Cohesion in Mice Aged Up to 15 Months1

3 Nov 2011

Abstract excerpt

Human eggs are highly aneuploid, with female age being the only known risk factor. Here this aging phenomenon was further studied in Swiss CD1 mice aged between 1 and 15 mo. The mean number of eggs ± SEM recovered from mice following superovulation peaked at 22.5 ± 3.8 eggs/oviduct in 3-mo-old females, decreasing markedly between 6 and 9 mo old, and was only 2.1 ± 0.2 eggs/oviduct by 15 mo. Measurement of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Kidney Cyst Diseases
Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22053097
DOI: 10.1095/biolreprod.111.095711

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of Aging on Superovulation Efficiency, Aneuploidy Rates, and Sister Chromatid Cohesion in Mice Aged Up to 15 Months1PMID 22053097Read ↗

Chromosome cohesion decreases in human eggs with advanced maternal ageSemantic proximity Read ↗

Evidence That a Defective Spindle Assembly Checkpoint Is Not the Primary Cause of Maternal Age-Associated Aneuploidy in Mouse Eggs1Semantic proximity Read ↗

Ovulation suppression protects against chromosomal abnormalities in mouse eggs at advanced maternal ageSemantic proximity Read ↗

Chromosome errors in human eggs shape natural fertility over reproductive life spanSemantic proximity Read ↗

Next Generation Sequencing-Based Comprehensive Chromosome Screening in Mouse Polar Bodies, Oocytes, and Embryos1Semantic proximity Read ↗

Meiotic Origins of Maternal Age-Related Aneuploidy1Semantic proximity Read ↗

Actin limits egg aneuploidies associated with female reproductive agingSemantic proximity Read ↗

Chromosome Ageing Occurs at the Primordial Follicle Stage in both Mouse and Human OocytesSemantic proximity Read ↗

Age-Dependent Susceptibility of Chromosome Cohesion to Premature Separase Activation in Mouse Oocytes1Semantic proximity Read ↗

Age‐dependent aneuploidy in mammalian oocytes instigated at the second meiotic divisionSemantic proximity Read ↗

Distinct classes of lagging chromosome underpin age-related oocyte aneuploidy in mouseSemantic proximity Read ↗

Reduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.