Article

Computing MicroRNA-Gene Interaction Networks in Pan-cancer Using MiRDriver

2021-12-06

Abstract excerpt

DNA copy number aberrated regions in cancer are known to harbor cancer driver genes and the short non-coding RNA molecules, i.e ., microRNAs. In this study, we integrated the multi-omics datasets such as copy number aberration, DNA methylation, gene and microRNA expression to identify the signature microRNA-gene associations from frequently aberrated DNA regions across pan-cancer utilizing a LASSO-based regression...

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Literature Corpus work: d749f6e5-93a1-5198-b5d2-638dcb6a2903
DOI: 10.21203/rs.3.rs-1101651/v1

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