Article
Several RNase T2 enzymes function in induced tRNA and rRNA turnover in the ciliate Tetrahymena.
Molecular biology of the cell - 1 Jan 2012
Andersen Kasper L, Collins Kathleen
Abstract excerpt
RNase T2 enzymes are produced by a wide range of organisms and have been implicated to function in diverse cellular processes, including stress-induced anticodon loop cleavage of mature tRNAs to generate tRNA halves. Here we describe a family of eight RNase T2 genes (RNT2A-RNT2H) in the ciliate Tetrahymena thermophila. We constructed strains lacking individual or combinations of these RNT2 genes that were viable...
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