Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hibernation factors directly block ribonucleases from entering the ribosome in response to starvation.

Nucleic acids research - 26 Feb 2021

Prossliner Thomas, Gerdes Kenn, Sørensen Michael Askvad, Winther Kristoffer Skovbo

Abstract excerpt

Ribosome hibernation is a universal translation stress response found in bacteria as well as plant plastids. The term was coined almost two decades ago and despite recent insights including detailed cryo-EM structures, the physiological role and underlying molecular mechanism of ribosome hibernation has remained unclear. Here, we demonstrate that Escherichia coli hibernation factors RMF, HPF and RaiA (HFs)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carbon
Share to Escherichia coli Proteins
Share to Protein Biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ribonucleases

Share to Ribosomal Proteins

Share to Ribosomes

Share to RNA, Ribosomal, 16S

Share to Stress, Physiological

Source

Open in PubMed Open full text

Identifiers

PMID: 33503254
DOI: 10.1093/nar/gkab017
PMCID: PMC7913689

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hibernation factors directly block ribonucleases from entering the ribosome in response to starvation.PMID 33503254Read ↗

A bacterial ribosome hibernation factor with evolutionary connections to eukaryotic protein synthesisSemantic proximity Read ↗

Regulation of ribosome hibernation controls Legionella survival, infection, antibiotic tolerance, and phenotypic heterogeneity.Semantic proximity Read ↗

Ribosome hibernation factor promotes Staphylococcal survival and differentially represses translation.Semantic proximity Read ↗

Mechanistic insights into <i>E. coli</i> recovery from growth arrestSemantic proximity Read ↗

Cotranslational response to proteotoxic stress by elongation pausing of ribosomes.Semantic proximity Read ↗

Functional Characterization of the Pseudomonas aeruginosa Ribosome Hibernation-Promoting Factor.Semantic proximity Read ↗

SrmB Rescues Trapped Ribosome Assembly Intermediates.Semantic proximity Read ↗

A family of RRM-1 RNA binding proteins enables cold adaptation and environmental resilience in <i>Bacteroides</i>Semantic proximity Read ↗

Visualizing formation of the active site in the mitochondrial ribosome.Semantic proximity Read ↗

A Conserved Obg-type GTPase sustains protein synthesis and its physiological roles in eukaryotic cellsSemantic proximity Read ↗

Evidence for in vivo ribosome recycling, the fourth step in protein biosynthesis.Semantic proximity Read ↗

RNA degradation analysis reveals ribosome dynamics in complex microbiome samplesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.