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Article

Identification and Characterization of Base-Substitution Mutations in the Macronuclear Genome of the Ciliate Tetrahymena thermophila.

Genome biology and evolution - 7 Jan 2021

Wang Guangying, Fu Lu, Xiong Jie, Mochizuki Kazufumi, Fu Yunxin, Miao Wei

Abstract excerpt

Polyploidy can provide adaptive advantages and drive evolution. Amitotic division of the polyploid macronucleus (MAC) in ciliates acts as a nonsexual genetic mechanism to enhance adaptation to stress conditions and thus provides a unique model to investigate the evolutionary role of polyploidy. Mutation is the primary source of the variation responsible for evolution and adaptation; however, to date, de novo...

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Identifiers

PMID: 33146387
DOI: 10.1093/gbe/evaa232
PMCID: PMC7788487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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