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Article

A mutant of human immunodeficiency virus with reduced RNA packaging and abnormal particle morphology.

Journal of virology - 1 Oct 1990

Clavel F, Orenstein J M

Abstract excerpt

A deletion of 30 bases was created in the noncoding region of the human immunodeficiency virus type 1 genome that extends between the 5' splice donor and the start of the gag gene. Viral particles produced after transfection of this mutant provirus had a normal protein pattern but a reduced RNA c...

Topics

Base Sequence
Cell Line
Chromosome Deletion
Gene Products, gag
Genes, Viral
HIV-1
Humans
Microscopy, Electron
Molecular Sequence Data
Mutation
RNA Splicing
RNA, Viral
Transfection

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Identifiers

PMID: 2204725
DOI: 10.1128/JVI.64.10.5230-5234.1990
PMCID: PMC248025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2204725-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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