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Article

The role of Gag in human immunodeficiency virus type 1 virion morphogenesis and early steps of the viral life cycle

1 Dec 1996

Abstract excerpt

The phenotypes of a series of mutant human immunodeficiency virus type 1 proviruses with linker insertion and deletion mutations within the gag coding region were characterized. These mutants, with mutations in the matrix, capsid, and p2 coding regions, produced replication-defective virion particles with defects in the early steps of the viral life cycle. To investigate this phenotype further, the abilities of...

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PMID: 8970990
DOI: 10.1128/jvi.70.12.8645-8652.1996

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