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Article

Conditional infectivity of a human immunodeficiency virus matrix domain deletion mutant.

Journal of virology - 1 Dec 1993

Wang C T, Zhang Y, McDermott J, Barklis E

Abstract excerpt

We constructed a human immunodeficiency virus (HIV) matrix (MA) deletion mutant by deletion of about 80% of the HIV type 1 Gag MA domain but retaining myristylation and proteolytic processing signals. The effects of this deletion matrix (dl.MA) mutant on HIV particle assembly, processing, and infectivity were analyzed. Surprisingly, the dl.MA mutant still could assemble and process virus particles, had a...

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Identifiers

PMID: 7693966
DOI: 10.1128/JVI.67.12.7067-7076.1993
PMCID: PMC238168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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