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Article

The CDKN2A G500 allele is more frequent in GBM patients with no defined telomere maintenance mechanism tumors and is associated with poorer survival.

PloS one - 1 Jan 2011

Royds Janice A, Al Nadaf Shafagh, Wiles Anna K, Chen Yu-Jen, Ahn Antonio, Shaw Alisha, Bowie Sara, Lam Frederic, Baguley Bruce C, Braithwaite Antony W, MacFarlane Martin R, Hung Noelyn A, Slatter Tania L

Abstract excerpt

Prognostic markers for glioblastoma multiforme (GBM) are important for patient management. Recent advances have identified prognostic markers for GBMs that use telomerase or the alternative lengthening of telomeres (ALT) mechanism for telomere maintenance. Approximately 40% of GBMs have no defined telomere maintenance mechanism (NDTMM), with a mixed survival for affected individuals. This study examined genetic...

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Identifiers

PMID: 22046342
DOI: 10.1371/journal.pone.0026737
PMCID: PMC3202568

Genes

IDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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