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Survival Impact of Isocitrate Dehydrogenase (IDH)-Wildtype Histological Versus Molecular Glioblastoma: A Propensity Score-Matched Analysis

24 Jul 2025

Abstract excerpt

Introduction Glioblastoma (GBM) is a highly aggressive brain tumor with a poor prognosis. Molecular classification has redefined GBM subtypes, but survival differences between histological GBM (h-GBM) and molecular GBM (mol-GBM) remain underexplored. This study uses propensity score matching (PSM) to compare survival outcomes, accounting for clinical confounders. Methods A retrospective cohort of isocitrate...

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PMID: 40861724
DOI: 10.7759/cureus.88667

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